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Surgical Oncology Program »  Research »  Clinical Trials

Clinical Trials

Below is a listing of GI Oncology clinical trials as well as selected Phase I studies for solid tumors. You may also wish to review our primer on Participating in Clinical Trials. 

   Also show trials not enrolling patients
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RecruitingActive, but closed to enrollmentRecruitingRecruitingActive, not recruitingRecruitingActive, not recruitingCompletedNot yet recruitingActive, not recruitingRecruitingActive, not recruitingActive, but closed to enrollmentRecruitingRecruitingActive, not recruitingRecruitingRecruitingRecruitingActive, not recruitingActive, not recruitingRecruitingRecruitingRecruitingRecruitingRecruitingNot yet recruitingActive, not recruitingActive, but closed to enrollmentRecruitingActive, not recruitingRecruitingRecruitingActive, not recruitingActive, not recruitingActive, not recruitingRecruitingRecruitingRecruitingRecruitingActive, not recruitingRecruitingRecruiting

Carcinoid Tumor

RecruitingActive, but closed to enrollmentRecruiting
A Study of Axitinib in Advanced Carcinoid Tumors
Study ID: UCSF-114520
Principal Investigator:
Emily Bergsland, M.D.
Enrolling patients
RecruitingActive, not recruitingRecruitingActive, not recruitingCompletedNot yet recruitingActive, not recruitingRecruitingActive, not recruitingActive, but closed to enrollmentRecruitingRecruitingActive, not recruitingRecruitingRecruitingRecruitingActive, not recruitingActive, not recruitingRecruitingRecruitingRecruitingRecruitingRecruitingNot yet recruitingActive, not recruitingActive, but closed to enrollmentRecruitingActive, not recruitingRecruitingRecruitingActive, not recruitingActive, not recruitingActive, not recruitingRecruitingRecruitingRecruitingRecruitingActive, not recruitingRecruitingRecruiting

Colorectal Cancer

RecruitingActive, but closed to enrollmentRecruitingRecruitingActive, not recruitingRecruitingActive, not recruitingCompletedNot yet recruitingActive, not recruitingRecruitingActive, not recruitingActive, but closed to enrollmentRecruitingRecruitingActive, not recruitingRecruitingRecruiting
Efficacy Evaluation of TheraSphere Following Failed First Line Chemotherapy in Metastatic Colorectal Cancer
Study ID: UCSF-12451
Principal Investigator:
Nicholas Fidelman, M.D.
Enrolling patients
RecruitingActive, not recruitingActive, not recruitingRecruitingRecruiting
Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery
Study ID: CALGB-80702
Principal Investigator:
Alan P. Venook, M.D.
Enrolling patients
RecruitingRecruitingRecruitingNot yet recruitingActive, not recruitingActive, but closed to enrollmentRecruitingActive, not recruitingRecruitingRecruitingActive, not recruitingActive, not recruitingActive, not recruitingRecruitingRecruitingRecruitingRecruitingActive, not recruitingRecruiting
Yttrium-90 Radioembolization Using Glass Microspheres (TheraSphere) for Patients With Liver Metastases
Study ID: UCSF-08451-B
Principal Investigator:
Nicholas Fidelman, M.D.
Enrolling patients
Recruiting

Hepatocellular Carcinoma (Primary Liver Cancer)

RecruitingActive, but closed to enrollmentRecruitingRecruitingActive, not recruitingRecruitingActive, not recruitingCompletedNot yet recruitingActive, not recruitingRecruitingActive, not recruitingActive, but closed to enrollmentRecruiting
Chemoembolization With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery
Study ID: ECOG-E1208
Principal Investigator:
Alan P. Venook, M.D.
Enrolling patients
RecruitingActive, not recruitingRecruitingRecruitingRecruitingActive, not recruitingActive, not recruitingRecruitingRecruitingRecruitingRecruitingRecruitingNot yet recruitingActive, not recruitingActive, but closed to enrollmentRecruitingActive, not recruitingRecruitingRecruiting
Sorafenib Tosylate With or Without Doxorubicin Hydrochloride in Treating Patients With Locally Advanced or Metastatic Liver Cancer
Study ID: CALGB-80802
Principal Investigator:
Alan P. Venook, M.D.
Enrolling patients
Active, not recruitingActive, not recruitingActive, not recruitingRecruiting
Study of REGN910 (SAR307746)
Study ID: UCSF-09455
Principal Investigator:
R. Kate (Katie) Kelley, M.D.
Enrolling patients
RecruitingRecruitingRecruitingActive, not recruitingRecruitingRecruiting
Yttrium-90 Radioembolization With Glass Microspheres (TheraSphere) for Patients With Hepatocellular Carcinoma
Study ID: UCSF-08451-A
Principal Investigator:
Nicholas Fidelman, M.D.
Enrolling patients

Liver Metastases

RecruitingActive, but closed to enrollmentRecruitingRecruitingActive, not recruitingRecruitingActive, not recruitingCompletedNot yet recruitingActive, not recruitingRecruitingActive, not recruitingActive, but closed to enrollmentRecruitingRecruitingActive, not recruitingRecruitingRecruiting
Efficacy Evaluation of TheraSphere Following Failed First Line Chemotherapy in Metastatic Colorectal Cancer
Study ID: UCSF-12451
Principal Investigator:
Nicholas Fidelman, M.D.
Enrolling patients
RecruitingActive, not recruitingActive, not recruitingRecruitingRecruitingRecruitingRecruitingRecruitingNot yet recruitingActive, not recruitingActive, but closed to enrollmentRecruitingActive, not recruitingRecruitingRecruitingActive, not recruitingActive, not recruitingActive, not recruitingRecruitingRecruitingRecruitingRecruitingActive, not recruitingRecruiting
Yttrium-90 Radioembolization Using Glass Microspheres (TheraSphere) for Patients With Liver Metastases
Study ID: UCSF-08451-B
Principal Investigator:
Nicholas Fidelman, M.D.
Enrolling patients
Recruiting

Melanoma

RecruitingActive, but closed to enrollmentRecruitingRecruitingActive, not recruitingRecruitingActive, not recruitingCompletedNot yet recruitingActive, not recruitingRecruitingActive, not recruitingActive, but closed to enrollmentRecruitingRecruitingActive, not recruitingRecruitingRecruitingRecruitingActive, not recruitingActive, not recruitingRecruitingRecruitingRecruitingRecruitingRecruitingNot yet recruitingActive, not recruitingActive, but closed to enrollmentRecruitingActive, not recruitingRecruitingRecruitingActive, not recruitingActive, not recruitingActive, not recruitingRecruitingRecruitingRecruitingRecruitingActive, not recruitingRecruiting
Yttrium-90 Radioembolization Using Glass Microspheres (TheraSphere) for Patients With Liver Metastases
Study ID: UCSF-08451-B
Principal Investigator:
Nicholas Fidelman, M.D.
Enrolling patients
Recruiting

Neuroendocrine Tumors

RecruitingActive, but closed to enrollmentRecruitingRecruitingActive, not recruitingRecruitingActive, not recruitingCompletedNot yet recruitingActive, not recruitingRecruitingActive, not recruitingActive, but closed to enrollmentRecruitingRecruitingActive, not recruitingRecruitingRecruitingRecruitingActive, not recruitingActive, not recruitingRecruitingRecruitingRecruitingRecruitingRecruitingNot yet recruitingActive, not recruitingActive, but closed to enrollmentRecruitingActive, not recruitingRecruitingRecruitingActive, not recruitingActive, not recruitingActive, not recruitingRecruitingRecruitingRecruitingRecruitingActive, not recruitingRecruiting
Yttrium-90 Radioembolization Using Glass Microspheres (TheraSphere) for Patients With Liver Metastases
Study ID: UCSF-08451-B
Principal Investigator:
Nicholas Fidelman, M.D.
Enrolling patients
Recruiting

Pancreatic Cancer

RecruitingActive, but closed to enrollmentRecruitingRecruitingActive, not recruitingRecruitingActive, not recruitingCompletedNot yet recruitingActive, not recruitingRecruiting
AZD6244 and Erlotinib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
Study ID: UCSF-10454
Principal Investigator:
Andrew H. Ko, M.D.
Enrolling patients
Active, not recruitingActive, but closed to enrollmentRecruitingRecruitingActive, not recruitingRecruitingRecruitingRecruitingActive, not recruitingActive, not recruitingRecruitingRecruitingRecruitingRecruitingRecruitingNot yet recruitingActive, not recruitingActive, but closed to enrollmentRecruitingActive, not recruitingRecruitingRecruitingActive, not recruitingActive, not recruitingActive, not recruitingRecruitingRecruitingRecruitingRecruitingActive, not recruitingRecruitingRecruiting

Rectal Cancer

RecruitingActive, but closed to enrollmentRecruitingRecruitingActive, not recruitingRecruitingActive, not recruitingCompletedNot yet recruitingActive, not recruitingRecruitingActive, not recruitingActive, but closed to enrollmentRecruitingRecruiting
Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery
Study ID: Alliance N1048
Principal Investigator:
Alan P. Venook, M.D.
Enrolling patients
Active, not recruitingRecruitingRecruitingRecruitingActive, not recruitingActive, not recruitingRecruitingRecruitingRecruitingRecruitingRecruitingNot yet recruitingActive, not recruitingActive, but closed to enrollmentRecruitingActive, not recruitingRecruitingRecruitingActive, not recruitingActive, not recruitingActive, not recruitingRecruitingRecruitingRecruitingRecruitingActive, not recruitingRecruitingRecruiting

Solid Tumor

Recruiting
A Safety Study of MM-121 With Cetuximab and Irinotecan in Patients With Advanced Cancers
Study ID: UCSF-11956
Principal Investigator:
W. Michael Korn, M.D.
Enrolling patients
Active, but closed to enrollmentRecruitingRecruiting
A Study of IMC-CS4 in Subjects With Advanced Solid Tumors
Study ID: UCSF-11993
Principal Investigator:
Hope Rugo, M.D.
Enrolling patients
Active, not recruitingRecruiting
A Study of LY2875358 in Patients With Advanced Cancer
Study ID: UCSF-109910
Principal Investigator:
Alain Algazi, M.D.
Enrolling patients
Active, not recruitingCompletedNot yet recruiting
A Study of the Safety and Pharmacokinetics of AGS-22M6E in Subjects With Malignant Solid Tumors That Express Nectin-4
Study ID: UCSF-12955
Principal Investigator:
Hope Rugo, M.D.
Not yet enrolling
Active, not recruitingRecruitingActive, not recruitingActive, but closed to enrollmentRecruitingRecruitingActive, not recruitingRecruiting
Dose-Escalation Study of GSK2126458
Study ID: UCSF-09992
Principal Investigator:
Pamela Munster, M.D.
Enrolling patients
RecruitingRecruiting
Eribulin in Combination With Cyclophosphamide in Patients With Solid Tumor Malignancies
Study ID: UCSF-11996
Principal Investigator:
Hope Rugo, M.D.
Enrolling patients
Active, not recruitingActive, not recruitingRecruiting
MK-2206, Paclitaxel and Trastuzumab in Treating Patients With HER2-overexpressing Solid Tumor Malignancies
Study ID: UCSF-10998
Principal Investigator:
A. Jo Chien, M.D.
Enrolling patients
RecruitingRecruiting
Panobinostat and Epirubicin in Treating Patients With Metastatic Malignant Solid Tumors
Study ID: UCSF-09991
Principal Investigator:
Pamela Munster, M.D.
Enrolling patients
Recruiting
Phase I Tolerability, Efficacy, and Safety Study of Pazopanib in Combination With PCI-24781 in Patients With Metastatic Solid Tumors
Study ID: UCSF-11955
Principal Investigator:
Pamela Munster, M.D.
Enrolling patients
Recruiting
Phase I/Ib Dose-escalation of Dinaciclib With Weekly Paclitaxel for Advanced Solid Tumor Malignancies & Assessment of MYC Oncogene Overexpression
Study ID: UCSF-12951
Principal Investigator:
A. Jo Chien, M.D.
Enrolling patients
Not yet recruiting
Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors
Study ID: NCT01576666
Principal Investigator:
Pamela Munster, M.D.
Not yet enrolling
Active, not recruitingActive, but closed to enrollmentRecruiting
Safety and Tolerability of Different Dose Combinations of Ridaforolimus With MK-2206 or MK-0752 for Participants With Advanced Cancer (MK-8669-049 AM1)
Study ID: UCSF-11991
Principal Investigator:
Pamela Munster, M.D.
Enrolling patients
Active, not recruitingRecruiting
Safety Study of PLX3397 and Paclitaxel in Patients With Advanced Solid Tumors
Study ID: UCSF-12953
Principal Investigator:
Hope Rugo, M.D.
Enrolling patients
RecruitingActive, not recruitingActive, not recruitingActive, not recruitingRecruitingRecruiting
Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, Non-Hodgkin's Lymphoma or Multiple Myeloma
Study ID: UCSF-11995
Principal Investigator:
Pamela Munster, M.D.
Enrolling patients
Recruiting
Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, Non-Hodgkin's Lymphoma or Multiple Myeloma
Study ID: UCSF-11954
Principal Investigator:
Pamela Munster, M.D.
Enrolling patients
Recruiting
Study to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple Myeloma
Study ID: UCSF-10993
Principal Investigator:
Pamela Munster, M.D.
Enrolling patients
Active, not recruitingRecruitingRecruitingRecruitingActive, but closed to enrollmentRecruitingRecruitingActive, not recruitingRecruitingActive, not recruitingCompletedNot yet recruitingActive, not recruitingRecruitingActive, not recruitingActive, but closed to enrollmentRecruitingRecruitingActive, not recruitingRecruitingRecruitingRecruitingActive, not recruitingActive, not recruitingRecruitingRecruitingRecruitingRecruitingRecruitingNot yet recruitingActive, not recruitingActive, but closed to enrollmentRecruitingActive, not recruitingRecruitingRecruitingActive, not recruitingActive, not recruitingActive, not recruitingRecruitingRecruitingRecruitingRecruitingActive, not recruitingRecruitingRecruiting
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